Browsing by Author "Valiente Echeverría, Fernando Andrés"

Now showing items 1-10 of 10

    • Early versus deferred anti-SARS-CoV-2 convalescent plasma in patients admitted for COVID-19: A randomized ... 
      Balcells, María Elvira; Rojas, Luis; Le Corre, Nicole; Martínez Valdebenito, Constanza; Ceballos, María Elena; Ferrés, Marcela; Chang, Mayling; Vizcaya, Cecilia; Mondaca, Sebastián; Huete, Álvaro; Castro, Ricardo; Sarmiento, Mauricio; Villarroel, Luis; Pizarro, Alejandra; Ross, Patricio; Santander, Jaime; Lara, Bárbara; Ferrada, Marcela; Vargas Salas, Sergio Sebastián; Beltrán Pavez, Carolina Alejandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés; Caglevic, Christian; Mahave, Mauricio; Selman, Carolina; Gazitua, Raimundo; Briones, José Luis; Villarroel Espíndola, Franz; Balmaceda, Carlos; Espinoza, Manuel A.; Pereira, Jaime; Nervi, Bruno (Public Library Science, 2021)
      Background Convalescent plasma (CP), despite limited evidence on its efficacy, is being widely used as a compassionate therapy for hospitalized patients with COVID-19. We aimed to evaluate the efficacy and safety of ...
    • Emerging roles of N - 6 - methyladenosine on HIV - 1 RNA metabolism and viral replication 
      Riquelme Barrios, Sebastián; Pereira Montecinos, Camila; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo (Frontiers Media, 2018)
      N-6-methyladenosine (m(6)A) is the most abundant internal modification present in Eukaryotic mRNA. The functions of this chemical modification are mediated by m(6)-Abinding proteins (m(6)A readers) and regulated by ...
    • HIV-2 genomic RNA accumulates in stress granules in the absence of active translation 
      Soto Rifo, Ricardo; Valiente Echeverría, Fernando Andrés; Rubilar, Paulina S.; Garcia-de-Gracia, Francisco; Ricci, Emiliano P.; Limousin, Taran; Décimo, Didier; Mouland, Andrew J.; Ohlmann, Théophile (2014)
      During the post-transcriptional events of the HIV-2 replication cycle, the full-length unspliced genomic RNA (gRNA) is first used as an mRNA to synthesize Gag and Gag-Pol proteins and then packaged into progeny virions. ...
    • Implementación de un sistema pseudoviral que permita determinar anticuerpos neutralizantes contra los ... 
      Ceballos Román, María Alejandra (Universidad de Chile, 2022)
      Cuatro coronavirus de dos géneros distintos son endémicos en los humanos: dos alfacoronavirus (NL63 y 229E) y dos betacoronavirus (OC43 y HKU1), causan frecuentemente enfermedades leves del tracto respiratorio superior ...
    • Insights into neutralizing antibody responses in individuals exposed to SARS-CoV-2 in Chile 
      Beltrán Pavez, Carolina Alejandra; Riquelme Barrios, Sebastian Andres; Oyarzún Arrau, Aarón; Gaete Argel, Aracelly Janis; González Stegmaier, Roxana; Cereceda Solis, Karina; Aguirre, Adam; Travisany Flores, Dante Felipe; Palma Vejares, Ricardo Fernando; Barriga Pinto, Gonzalo Andrés; Gaggero Brillouet, Aldo Andres; Martínez Valdebenito, Constanza; Le Corre, Nicole; Ferres Garrido, Marcela Viviana; Balcells, María Elvira; Fernández, Jorge; Ramírez, Eugenio; Villarroel, Franz; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés (American Association for the Advancement of Science, 2021)
      Chile has one of the worst numbers worldwide in terms of SARS-CoV-2 positive cases and COVID-19-related deaths per million inhabitants; thus, characterization of neutralizing antibody (NAb) responses in the general population ...
    • N-6 -methyladenosine negatively regulates human respiratory syncytial virus replication 
      Figueroa, Fabián; Vega Gibson, Alonso Gonzalo; Catrileo, Joseline; Gaete Argel, Aracelly Janis; Riquelme Barrios, Sebastián Andrés; Alonso Palomares, Luis Antonio; Tapia Faúndes, Lorena; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo Andrés; Acevedo Acevedo, Mónica Loreto (Frontiers Media, 2021)
      N 6 -methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV). Here, we evaluated the impact of m6A writers, ...
    • Neutralizing antibody titers elicited by CoronaVac and BNT162b2 vaccines in health care workers with and ... 
      Wolff Reyes, Marcelo José; Acevedo Acevedo, Mónica Loreto; Núñez, María Antonieta; Lafourcade, Mónica; Gaete Argel, Aracelly Janis; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Oxford University Press, 2022)
      We report neutralizing antibody titers (NAbTs) elicited by CoronaVac and BNT162b2 vaccines in healthcare workers with and without prior SARS-CoV-2 infection using both a pseudotype-based assay and a commercial kit. NAbTs ...
    • Performance of SARS-CoV-2 rapid antigen test compared with real-time RT-PCR in asymptomatic individuals 
      Peña, Mónica; Ampuero Martínez, Manuel Andrés; Garcés, Carlos; Gaggero Brillouet, Aldo Andres; García, Patricia; Velásquez, María Soledad; Luza, Ricardo; Álvarez, Pía; Paredes, Fabio; Acevedo, Johanna; Farfán Urzúa, Mauricio Javier; Solari, Sandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Elsevier, 2021)
      Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) ...
    • Seroconversion and abundance of IgG antibodies against S1-RBD of SARS-CoV-2 and neutralizing activity in ... 
      González Stegmaier, R.; Cereceda, K.; Briones, J. L.; Beltrán Pavez, C.; Oyarzún Arrau, A.; Riquelme Barrios, S.; Selman, C.; Yarad, F.; Mahave, M.; Caglevic, C.; Morales, R.; Aguirre, A.; Valiente Echeverría, Fernando Andrés; Soto Rifo, Ricardo; Marsiglia, H.; Gazitúa, R.; Villarroel Espíndola, F. (Hindawi, 2021)
      COVID-19 is a pandemic caused by SARS-CoV-2. In Chile, half a million people have been infected and more than 16,000 have died from COVID-19. As part of the clinical trial NCT04384588, we quantified IgG against S1-RBD of ...
    • Tellurite promotes stress granules and nuclear SG-like assembly in response to oxidative stress and DNA damage 
      Gaete Argel, Aracelly Janis; Velásquez, Felipe; Márquez Badilla, Chantal Loretto; Rojas Araya, Bárbara; Bueno Nieto, Constanza Francisca; Marín Rojas, Josefina; Cuevas Zúñiga, Miguel; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Frontiers Media, 2021)
      Tellurium oxyanion, tellurite (TeO3-2), is a highly toxic compound for many organisms. Its presence in the environment has increased over the past years due to industrial manufacturing processes and has been associated ...